Severe ARDS Escalation Workflow

VV ECMO referral decision support

VV ECMO Referral Criteria for severe ARDS

Screen severe ARDS patients for common VV ECMO referral triggers using P/F ratio, respiratory acidosis, ventilator intensity, rescue therapy status, and major contraindication cautions.

Use this workflow with the P/F Ratio calculator, Oxygenation Index calculator, ARDSNet calculator, and ABG Analyzer when deciding whether to call an ECMO center.

Step 01
Quantify oxygenation and ventilation failure
Step 02
Check prone/NMB rescue therapy status
Output
Call now, discuss early, optimize, or caution

Step 01

Gas exchange and ventilator intensity

Enter the values that define severe hypoxemic or hypercapnic respiratory failure.

Current P/F

Step 02

Rescue therapy status

Mark whether high-value ARDS rescue strategies have been attempted, are contraindicated, or are still unknown.

Prone positioning attempted or contraindicated

Severe ARDS patients often warrant prone positioning before ECMO when feasible.

Neuromuscular blockade / deep synchrony strategy considered

Use when ventilator dyssynchrony, high drive, or injurious ventilation is contributing.

Step 03

Major caution flags

Select factors that may limit ECMO candidacy or require specialist discussion before transfer.

How to use this VV ECMO referral tool

This tool is designed for early bedside escalation conversations in severe ARDS. It highlights severe hypoxemia, refractory hypercapnic acidosis, high ventilator intensity, incomplete rescue therapy, and major caution flags.

A positive referral trigger does not mean the patient automatically receives ECMO. It means the case may deserve timely discussion with an ECMO-capable center before prolonged injurious ventilation reduces candidacy.

Clinical caution

ECMO candidacy depends on reversibility, severity of non-pulmonary organ failure, neurologic prognosis, bleeding risk, duration of mechanical ventilation, frailty, local criteria, and goals of care.

Do not delay urgent specialist consultation when gas exchange is failing despite lung-protective ventilation, prone positioning, paralysis/synchrony strategies, and high-level ICU support.

Related PulmTools